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What is Pilocarpine?

Pilocarpine, as an ophthalmic agent that is used in the management of chronic simple glaucoma, chronic and acute angle-closure glaucoma. When given orally it is used to treat symptoms of dry mouth caused by decreased function of salivary glands.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
Sjogren's Syndrome 26 5 Efficacy_moderate Efficacy_slight Efficacy_none
Sjogrens syndrome 4 1 Efficacy_moderate
Dry mouth (xerostomia) 3 0
Dry eyes 1 0
Decreased saliva 1 1 Efficacy_moderate
Improve swallowing 1 0

See all 23 patients currently taking Pilocarpine

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Reported Side Effects

Side effects as an overall problem

Severe
2
Moderate
1
Mild
1
None
3

Commonly reported side effects, conditions, and hospitalizations associated with Pilocarpine

Sweating 1
Heart palpitations 1
Vertigo 1
Worsening vision 1

Reported Dosages

  3 5mg as needed 5 mg daily 7.5 mg daily 10 mg daily 15 mg daily 20 mg daily 22.5 mg daily 30 mg daily
  1 Number of Patients: 1 5 Number of Patients: 5 1 Number of Patients: 1 3 Number of Patients: 3 7 Number of Patients: 7 4 Number of Patients: 4 1 Number of Patients: 1 1 Number of Patients: 1  

Reported Stop Reasons

Why Patients Stopped Taking Pilocarpine (multiple reasons could be selected)
Reason # Patients Percentage of patients
Doctor's advice 5   Doctor's advice: 36%
Side effects too severe 5   Side effects too severe: 36%
Did not seem to work 4   Did not seem to work: 29%
Other 3   Other: 21%
Expense 1   Expense: 7%

See all 14 patients who’ve stopped taking Pilocarpine

Currently Taking Pilocarpine

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Stopped Taking Pilocarpine

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations

Adherence

Taking treatment as prescribed

Adherence of Pilocarpine

Always
4 57%
Usually
2 29%
Sometimes
0 0%
Never
1 14%

Burden

Difficulty being on treatment

Burden of Pilocarpine

Very
0 0%
Somewhat
2 29%
A little
3 43%
Not at all
2 29%

Cost

Paid out of pocket

Cost of Pilocarpine

$200+
0 0%
$100-199
0 0%
$50-99
0 0%
$25-49
0 0%
< $25
5 100%

See more information, including instructions, precautions, side effects, and interactions.

Report created on May 24, 2012.