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Home > Community Treatment Reports and Side Effects > Dextromethorphan with Quinidine Treatment Report
What is Dextromethorphan with Quinidine?

A dextromethorphan-quinidine combination was studied for its effect on inappropriate laughing and crying episodes experienced by some patients with brain injury or brain degeneration due to certain diseases. The incongruous laughing and crying episodes are due to pseudobulbar affect.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
Emotional lability 30 8 Efficacy_major Efficacy_moderate Efficacy_none
emotions, to stop uncontrollable laughing and crying 7 4 Efficacy_major Efficacy_moderate Efficacy_none
ALS (Amyotrophic Lateral Sclerosis) 4 0
Other 2 1 Efficacy_none
Slurred speech 2 1 Efficacy_moderate
Fatigue 1 0

See all 41 patients currently taking Dextromethorphan with Quinidine

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Reported Side Effects

Side effects as an overall problem

Severe
 1
Moderate
 4
Mild
 1
None
 10

Commonly reported side effects, conditions, and hospitalizations associated with Dextromethorphan with Quinidine

Fatigue 1
Dizziness 1
Diarrhea 1
Thrush 1
Heart palpitations 1
Sleepiness 1
See all 7 reported side effects ▼ See top 6 reported side effects ▲

Reported Dosages

Frequently reported dosages based on patients currently taking Dextromethorphan with Quinidine. See all 16 dosages ►

  daily 2 cap(s) daily 2 mg daily 10 mg daily 20 mg daily 25 mg daily 30 mg daily 40 mg daily 50 mg daily 60 mg daily
  5 Number of Patients: 5 6 Number of Patients: 6 3 Number of Patients: 3 4 Number of Patients: 4 4 Number of Patients: 4 1 Number of Patients: 1 3 Number of Patients: 3 4 Number of Patients: 4 3 Number of Patients: 3 5 Number of Patients: 5  

Reported Stop Reasons

Why Patients Stopped Taking Dextromethorphan with Quinidine (multiple reasons could be selected)
Reason # Patients Percentage of patients
Did not seem to work 2   Did not seem to work: 25%
Expense 2   Expense: 25%
Side effects too severe 2   Side effects too severe: 25%
Course of treatment ended 2   Course of treatment ended: 25%
Other 1   Other: 13%

See all 8 patients who’ve stopped taking Dextromethorphan with Quinidine

Reported Duration See details about how long patients take this treatment ▼

Currently Taking Dextromethorphan with Quinidine

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0

Stopped Taking Dextromethorphan with Quinidine

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0

Reported Adherence, Burden & Cost See details from patient evaluations ▼

Adherence

Taking treatment as prescribed

Adherence of Dextromethorphan with Quinidine

Always
 13 81%
Usually
 2 13%
Sometimes
 0 0%
Never
 1 6%

Burden

Difficulty being on treatment

Burden of Dextromethorphan with Quinidine

Very
 0 0%
Somewhat
 0 0%
A little
 1 6%
Not at all
 15 94%

Cost

Paid out of pocket

Cost of Dextromethorphan with Quinidine

$200+
 0 0%
$100-199
 0 0%
$50-99
 3 30%
$25-49
 4 40%
< $25
 3 30%

Report created on February 09, 2012.