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What is Bupropion?

Bupropion, a norepinephrine and dopamine reuptake inhibitor (NDRI) antidepressant is used for the treatment of major depressive disorder, including seasonal affective disorder (SAD) and as an adjunct in smoking cessation. Off label used for Attention-deficit/hyperactivity and bipolar disorders.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
Depressed mood 1113 347 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Major Depressive Disorder 694 169 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Treat my mood condition(s) 369 105 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Dysthymia 149 39 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Anxious mood 94 27 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_cant_tell
Other 85 21 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell

See all 2203 patients currently taking Bupropion

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Reported Side Effects

Side effects as an overall problem

Severe
 113
Moderate
 138
Mild
 212
None
 310

Commonly reported side effects, conditions, and hospitalizations associated with Bupropion

Dry mouth (xerostomia) 74
Insomnia 42
Headaches 30
Shakiness 29
Agitation 25
Constipation 24
See all 258 reported side effects ▼ See top 6 reported side effects ▲

Reported Dosages

Frequently reported dosages based on patients currently taking Bupropion. See all 67 dosages ►

  75 mg daily 100 mg daily 150 mg daily 150 mg/24 hours daily 200 mg daily 2 x 150 mg/24 hours daily 300 mg/24 hours daily 300 mg daily 400 mg daily 450 mg daily
  89 Number of Patients: 89 154 Number of Patients: 154 332 Number of Patients: 332 249 Number of Patients: 249 163 Number of Patients: 163 70 Number of Patients: 70 480 Number of Patients: 480 410 Number of Patients: 410 77 Number of Patients: 77 111 Number of Patients: 111  

Reported Stop Reasons

Why Patients Stopped Taking Bupropion (multiple reasons could be selected)
Reason # Patients Percentage of patients
Did not seem to work 286   Did not seem to work: 34%
Side effects too severe 262   Side effects too severe: 32%
Doctor's advice 205   Doctor's advice: 25%
Other 165   Other: 20%
Expense 63   Expense: 8%
Course of treatment ended 51   Course of treatment ended: 6%
Personal research 37   Personal research: 4%
Change in health plan coverage 22   Change in health plan coverage: 3%
Not indicated 12   Not indicated: 1%

See all 769 patients who’ve stopped taking Bupropion

Reported Duration See details about how long patients take this treatment ▼

Currently Taking Bupropion

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Stopped Taking Bupropion

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations ▼

Adherence

Taking treatment as prescribed

Adherence of Bupropion

Always
 608 79%
Usually
 126 16%
Sometimes
 18 2%
Never
 21 3%

Burden

Difficulty being on treatment

Burden of Bupropion

Very
 40 5%
Somewhat
 41 5%
A little
 130 17%
Not at all
 562 73%

Cost

Paid out of pocket

Cost of Bupropion

$200+
 7 1%
$100-199
 12 2%
$50-99
 43 8%
$25-49
 77 15%
< $25
 368 72%

See more information, including instructions, precautions, side effects, and interactions.

Report created on May 24, 2012.