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Home > Community Treatment Reports and Side Effects > Amitriptyline Treatment Report
What is Amitriptyline?

Amitriptyline is a tricyclic antidepressant approved for the treatment of depression. Off label amitripyline is used for certain chronic and neuropathic (nerve) pain and for prevention of migraine headaches.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
Insomnia 415 124 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Fibromyalgia 374 118 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Pain 341 101 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Depressed mood 150 54 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Sleep problems 139 47 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Nerve pain (neuralgia) 117 49 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell

See all 1577 patients currently taking Amitriptyline

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Reported Side Effects

Side effects as an overall problem

Severe
 79
Moderate
 133
Mild
 158
None
 181

Commonly reported side effects, conditions, and hospitalizations associated with Amitriptyline

Dry mouth (xerostomia) 75
Weight gain 62
Grogginess 37
Excessive daytime sleepiness (somnolence) 32
Hangover effect 27
Drowsiness 20
See all 149 reported side effects ▼ See top 6 reported side effects ▲

Reported Dosages

Frequently reported dosages based on patients currently taking Amitriptyline. See all 62 dosages ►

  10 mg daily 20 mg daily 25 mg daily 30 mg daily 40 mg daily 50 mg daily 75 mg daily 100 mg daily 150 mg daily 200 mg daily
  332 Number of Patients: 332 130 Number of Patients: 130 342 Number of Patients: 342 59 Number of Patients: 59 21 Number of Patients: 21 366 Number of Patients: 366 108 Number of Patients: 108 145 Number of Patients: 145 38 Number of Patients: 38 19 Number of Patients: 19  

Reported Stop Reasons

Why Patients Stopped Taking Amitriptyline (multiple reasons could be selected)
Reason # Patients Percentage of patients
Did not seem to work 236   Did not seem to work: 39%
Side effects too severe 225   Side effects too severe: 37%
Doctor's advice 132   Doctor's advice: 22%
Other 95   Other: 16%
Course of treatment ended 25   Course of treatment ended: 4%
Personal research 23   Personal research: 4%
Not indicated 14   Not indicated: 2%
Expense 11   Expense: 2%
Change in health plan coverage 3   Change in health plan coverage: 0%

See all 575 patients who’ve stopped taking Amitriptyline

Reported Duration See details about how long patients take this treatment ▼

Currently Taking Amitriptyline

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Stopped Taking Amitriptyline

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations ▼

Adherence

Taking treatment as prescribed

Adherence of Amitriptyline

Always
 437 79%
Usually
 81 15%
Sometimes
 22 4%
Never
 11 2%

Burden

Difficulty being on treatment

Burden of Amitriptyline

Very
 33 6%
Somewhat
 36 7%
A little
 73 13%
Not at all
 409 74%

Cost

Paid out of pocket

Cost of Amitriptyline

$200+
 1 0%
$100-199
 2 1%
$50-99
 2 1%
$25-49
 7 2%
< $25
 335 97%

See more information, including instructions, precautions, side effects, and interactions.

Report created on May 23, 2012.