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What is Lacosamide?

Lacosamide is an anticonvulsant agent used for adjunctive therapy in the treatment of partial-onset seizures. Lacosamide was previously known as harkoseride and then SPM 927.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
Epilepsy 218 65 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Seizures (complex partial) 38 14 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Seizures 4 1 Efficacy_cant_tell
Muscle tightness with stiffness 4 1 Efficacy_slight
Nerve pain (neuralgia) 2 0
atonic seizures 1 0

See all 246 patients currently taking Lacosamide

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Reported Side Effects

Side effects as an overall problem

Severe
 15
Moderate
 19
Mild
 30
None
 16

Commonly reported side effects, conditions, and hospitalizations associated with Lacosamide

Dizziness 9
Double vision (diplopia) 8
Nausea 6
Excessive daytime sleepiness (somnolence) 5
Tiredness 4
Stomach upset 3
See all 94 reported side effects ▼ See top 6 reported side effects ▲

Reported Dosages

Frequently reported dosages based on patients currently taking Lacosamide. See all 28 dosages ►

  50 mg daily 100 mg daily 150 mg daily 200 mg/20 mL daily 200 mg daily 250 mg daily 300 mg daily 400 mg daily 2 x 200 mg/20 mL daily 600 mg daily
  13 Number of Patients: 13 46 Number of Patients: 46 6 Number of Patients: 6 9 Number of Patients: 9 58 Number of Patients: 58 5 Number of Patients: 5 29 Number of Patients: 29 43 Number of Patients: 43 17 Number of Patients: 17 9 Number of Patients: 9  

Reported Stop Reasons

Why Patients Stopped Taking Lacosamide (multiple reasons could be selected)
Reason # Patients Percentage of patients
Side effects too severe 23   Side effects too severe: 47%
Did not seem to work 19   Did not seem to work: 39%
Doctor's advice 11   Doctor's advice: 22%
Other 8   Other: 16%
Expense 6   Expense: 12%
Personal research 1   Personal research: 2%
Course of treatment ended 1   Course of treatment ended: 2%
Change in health plan coverage 1   Change in health plan coverage: 2%

See all 48 patients who’ve stopped taking Lacosamide

Reported Duration See details about how long patients take this treatment ▼

Currently Taking Lacosamide

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0

Stopped Taking Lacosamide

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations ▼

Adherence

Taking treatment as prescribed

Adherence of Lacosamide

Always
 75 94%
Usually
 3 4%
Sometimes
 1 1%
Never
 1 1%

Burden

Difficulty being on treatment

Burden of Lacosamide

Very
 5 6%
Somewhat
 6 8%
A little
 14 18%
Not at all
 55 69%

Cost

Paid out of pocket

Cost of Lacosamide

$200+
 5 9%
$100-199
 5 9%
$50-99
 3 6%
$25-49
 8 15%
< $25
 32 59%

See more information, including instructions, precautions, side effects, and interactions.

Report created on May 23, 2012.