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Home > Community Treatment Reports and Side Effects > Leflunomide Treatment Report
What is Leflunomide?

Leflunomide is a disease modifying antirheumatic drug used to treat active rheumatoid arthritis to reduce symptoms, retard structural damage and improve physical function. Also use as to prevent rejection in organ transplants. Off label it is used for cytomegalovirus disease.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
RA (Rheumatoid Arthritis) 121 31 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Rheumatoid Arthritis 11 2 Efficacy_major
Systemic Lupus Erythematosus 5 1 Efficacy_moderate
Psoriatic Arthritis 5 2 Efficacy_none Efficacy_cant_tell
BK virus 4 0
Polyoma Virus 1 0

See all 97 patients currently taking Leflunomide

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Reported Side Effects

Side effects as an overall problem

Severe
 10
Moderate
 9
Mild
 5
None
 13

Commonly reported side effects, conditions, and hospitalizations associated with Leflunomide

Diarrhea 3
Nausea 3
Hair loss 2
Elevated blood pressure 2
Elevated liver enzymes 1
Chest pain 1
See all 26 reported side effects ▼ See top 6 reported side effects ▲

Reported Dosages

  20 mg weekly 20 mg m,w,f 60 mg weekly 10 mg daily 20 mg daily 30 mg daily 40 mg daily 100 mg m,w,f 100 mg daily
  3 Number of Patients: 3 3 Number of Patients: 3 1 Number of Patients: 1 21 Number of Patients: 21 69 Number of Patients: 69 2 Number of Patients: 2 1 Number of Patients: 1 1 Number of Patients: 1 2 Number of Patients: 2  

Reported Stop Reasons

Why Patients Stopped Taking Leflunomide (multiple reasons could be selected)
Reason # Patients Percentage of patients
Side effects too severe 32   Side effects too severe: 46%
Did not seem to work 25   Did not seem to work: 36%
Doctor's advice 21   Doctor's advice: 30%
Other 6   Other: 9%
Personal research 2   Personal research: 3%
Expense 2   Expense: 3%
Course of treatment ended 2   Course of treatment ended: 3%
Not indicated 1   Not indicated: 1%

See all 61 patients who’ve stopped taking Leflunomide

Reported Duration See details about how long patients take this treatment ▼

Currently Taking Leflunomide

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Stopped Taking Leflunomide

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations ▼

Adherence

Taking treatment as prescribed

Adherence of Leflunomide

Always
 33 89%
Usually
 3 8%
Sometimes
 0 0%
Never
 1 3%

Burden

Difficulty being on treatment

Burden of Leflunomide

Very
 3 8%
Somewhat
 4 11%
A little
 4 11%
Not at all
 26 70%

Cost

Paid out of pocket

Cost of Leflunomide

$200+
 0 0%
$100-199
 2 9%
$50-99
 2 9%
$25-49
 2 9%
< $25
 17 74%

See more information, including instructions, precautions, side effects, and interactions.

Report created on May 22, 2012.