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Home > Community Treatment Reports and Side Effects > Carbidopa-Levodopa Treatment Report
What is Carbidopa-Levodopa?

Levodopa is a dopamine precursor used to treat the movement disorder symptoms of Parkinson's disease. Carbidopa is often included with levodopa-containing drugs in order to boost its efficacy by slowing down the metabolism of dopamine.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
Parkinson's Disease 1451 357 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Stiffness/Spasticity 76 22 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Tremor 56 26 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none
Slowness 46 17 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none
Other 43 14 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
MSA (Multiple System Atrophy) 41 14 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell

See all 1783 patients currently taking Carbidopa-Levodopa

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Reported Side Effects

Side effects as an overall problem

Severe
 24
Moderate
 117
Mild
 147
None
 172

Commonly reported side effects, conditions, and hospitalizations associated with Carbidopa-Levodopa

Dyskinesia 65
Nausea 56
Drowsiness 32
Stomach upset 23
Vivid dreams 15
Sleep problems 15
See all 166 reported side effects ▼ See top 6 reported side effects ▲

Reported Dosages

Frequently reported dosages based on patients currently taking Carbidopa-Levodopa. See all 205 dosages ►

  daily 25 mg daily 25 mg-100 mg daily 2 x 25 mg-100 mg daily 3 x 25 mg-100 mg daily 4 x 25 mg-100 mg daily 5 x 25 mg-100 mg daily 6 x 25 mg-100 mg daily 7 x 25 mg-100 mg daily 8 x 25 mg-100 mg daily
  55 Number of Patients: 55 43 Number of Patients: 43 167 Number of Patients: 167 75 Number of Patients: 75 259 Number of Patients: 259 157 Number of Patients: 157 77 Number of Patients: 77 122 Number of Patients: 122 29 Number of Patients: 29 64 Number of Patients: 64  

Reported Stop Reasons

Why Patients Stopped Taking Carbidopa-Levodopa (multiple reasons could be selected)
Reason # Patients Percentage of patients
Doctor's advice 86   Doctor's advice: 37%
Did not seem to work 61   Did not seem to work: 26%
Other 45   Other: 19%
Side effects too severe 37   Side effects too severe: 16%
Personal research 20   Personal research: 9%
Course of treatment ended 14   Course of treatment ended: 6%
Not indicated 9   Not indicated: 4%
Expense 3   Expense: 1%
Change in health plan coverage 1   Change in health plan coverage: 0%

See all 216 patients who’ve stopped taking Carbidopa-Levodopa

Reported Duration See details about how long patients take this treatment ▼

Currently Taking Carbidopa-Levodopa

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Stopped Taking Carbidopa-Levodopa

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations ▼

Adherence

Taking treatment as prescribed

Adherence of Carbidopa-Levodopa

Always
 334 73%
Usually
 102 22%
Sometimes
 11 2%
Never
 13 3%

Burden

Difficulty being on treatment

Burden of Carbidopa-Levodopa

Very
 17 4%
Somewhat
 75 16%
A little
 109 24%
Not at all
 259 56%

Cost

Paid out of pocket

Cost of Carbidopa-Levodopa

$200+
 4 1%
$100-199
 9 3%
$50-99
 18 6%
$25-49
 48 15%
< $25
 235 74%

See more information, including instructions, precautions, side effects, and interactions.

Report created on May 19, 2012.